Buy AM-6545 Cannabinoid receptor

$140.00 – $5,800.00

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Description

Buy AM-6545 cannabinoid receptor

Buy AM-6545 cannabinoid receptor. AM-6545 for sale is a drug which acts as a peripherally selective silent antagonist for the CB1 receptor and was developed for the treatment of obesity. Other cannabinoid antagonists such as rimonabant have been marketed for this application but have subsequently been withdrawn from sale because of centrally mediated side effects such as depression and nausea. Because buy AM-6545 online does not cross the blood–brain barrier to any significant extent, it does not produce these kinds of side effects, but has still been shown to effectively reduce appetite and food consumption in animal studies. Buy AM-6545 cannabinoid 

Buy AM-6545 is a peripherally active, cannabinoid receptor antagonist with limited brain penetration. AM6545 binds to CB1 and CB2 receptors with Kis of 1.7 nM and 523 nM, respectively. AM6545 is a neutral antagonist. AM6545 can be used for the research of obesity and its complications

Technical Information buy AM-6545 online
Formal Name
5-[4-(4-cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide
CAS Number
1245626-05-4
Molecular Formula
C26H23Cl2N5O3S
Formula Weight
556.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
  • DMF: 10 mg/ml
  • DMSO: 10 mg/ml
  • DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml
λmax
268 nm
SMILES
ClC1=CC(Cl)=C(N2N=C(C(NN3CCS(CC3)(=O)=O)=O)C(C)=C2C4=CC=C(C#CCCC#N)C=C4)C=C1
InChi Code
InChI=1S/C26H23Cl2N5O3S/c1-18-24(26(34)31-32-13-15-37(35,36)16-14-32)30-33(23-11-10-21(27)17-22(23)28)25(18)20-8-6-19(7-9-20)5-3-2-4-12-29/h6-11,17H,2,4,13-16H2,1H3,(H,31,34)
InChi Key
XBHQLFVDGLPBCK-UHFFFAOYSA-N
Shipping & Storage Information buy AM-6545 online
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
  • CB-13 – a peripherally selective cannabinoid agonist
  • O-2050 – a centrally active CB1 silent antagonist
  • Methylnaltrexone – a peripherally selective mu opioid receptor antagonist
  • TM-38837 – another peripherally selective cannabinoid antagonist

Additional information

Quantity

10g, 25g, 50g, 100g, 250g, 500g, 1kg

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